Budget Impact Analysis of Drug X for Disease Y patients in England and Wales

Welcome to the York Health Economic Consortium budget impact model. This app was developed to assess the budget impact of Drug X for Disease Y patients in England and Wales.

Background

Disease Y is a rare inherited disorder. The standard treatment is an adapted diet. Drug X has been developed to treat Disease Y but is not suitable for all people with the disease. This app will assess the budget impact of funding Drug X for Disease Y patients in England and Wales.

Info

This is an example budget impact model built using R Shiny. R Shiny utilises the power of the statistical software R while providing users with a point and click experience when interacting with models and thus avoids the need to interact with any R code. This type of model is ideal for those needing to take advantage of the power of a coding language while maintaining user friendliness. R Shiny models can be accessed via any web browser provided an appropriate server can be used to host the model.

Population

Use the inputs on this page to create the target population.

Scenarios

Patient scenario

Population to use

Total population:

Live births:

You have selected The size of this population is

In a population of this size we would estimate there are Disease Y patients, including adults and children.

Current population

Prevalence of Disease Y (%):

Number of Adults (%):

Changes in the population

Incidence rate of Disease Y (%):

The number of live births is

An estimated births will be affected by Disease Y.

Eligible population suitable for treatment

Adults who are eligible for Drug X treatment (%):

Paediatrics who are eligible for Drug X treatment (%):

Live births who are eligible for Drug X treatment (%):

Respond to Drug X treatment at 4 weeks

Proportion of patients who respond to Drug X (%):

The number of eligible adults is

The number of eligible paediatrics is

The number of eligible live births is

Target population

Uptake Rates

Use the inputs on this page to alter the market shares of Drug X.

Uptake of Drug X in Incidence Population (%)

Year 1

Year 2

Year 3

Year 4

Year 5

Uptake of Drug X in Prevalent Population (%)

Year 1

Year 2

Year 3

Year 4

Year 5

Patient numbers in a world without Drug X treatment

Patient numbers in a world with Drug X treatment

Cost Inputs

Use the inputs on this page to alter the market shares of Drug X.

Drug X cost reduction:

PAS (%):

Drug X + restricted diet (Prevalent population)*

* Based on the weighted cost of the proportion of the population above and below the age of 18.

Restricted diet (Prevalent population)*

* Based on the weighted cost of the proportion of the population above and below the age of 18.

Drug X + restricted diet (Incident population)

Restricted diet (Incident population)

Cost Calculations

This page shows the costs associated with Drug X based on the scenario chosen on the Population page.

Total costs in a world without Drug X treatment

Total costs in a world with Drug X treatment

Results

This page shows the costs associated with Drug X based on the scenario chosen on the Population page.

Summary of total annual costs with and without Drug X treatment based on market share data

Plot of total annual costs with and without Drug X treatment based on market share data